| December 11, 2021 | UFC 269: Oliveira vs. Poirier | Charles Oliveira | Submission | Loss |
| July 10, 2021 | UFC 264: Poirier vs. McGregor 3 | Conor McGregor | TKO - Doctor's Stoppage | Win |
| January 23, 2021 | UFC 257: Poirier vs. McGregor | Conor McGregor | KO/TKO | Win |
| June 27, 2020 | UFC Fight Night: Poirier vs. Hooker | Dan Hooker | Decision - Unanimous | Win |
| September 07, 2019 | UFC 242: Khabib vs. Poirier | Khabib Nurmagomedov | Submission | Loss |
| April 13, 2019 | UFC 236: Holloway vs. Poirier 2 | Max Holloway | Decision - Unanimous | Win |
| July 28, 2018 | UFC Fight Night: Alvarez vs. Poirier 2 | Eddie Alvarez | KO/TKO | Win |
| April 14, 2018 | UFC Fight Night: Poirier vs. Gaethje | Justin Gaethje | KO/TKO | Win |
| November 11, 2017 | UFC Fight Night: Poirier vs. Pettis | Anthony Pettis | KO/TKO | Win |
| May 13, 2017 | UFC 211: Miocic vs. Dos Santos | Eddie Alvarez | Could Not Continue | Win |
| February 11, 2017 | UFC 208: Holm vs. De Randamie | Jim Miller | Decision - Majority | Win |
| September 17, 2016 | UFC Fight Night: Poirier vs. Johnson | Michael Johnson | KO/TKO | Loss |
| June 04, 2016 | UFC 199: Rockhold vs. Bisping 2 | Bobby Green | KO/TKO | Win |
| January 02, 2016 | UFC 195: Lawler vs Condit | Joe Duffy | Decision - Unanimous | Win |
| June 06, 2015 | UFC Fight Night: Boetsch vs Henderson | Yancy Medeiros | KO/TKO | Win |
| April 04, 2015 | UFC Fight Night: Mendes vs Lamas | Diego Ferreira | KO/TKO | Win |
| September 27, 2014 | UFC 178: Johnson vs Cariaso | Conor McGregor | KO/TKO | Loss |
| April 16, 2014 | UFC Fight Night: Bisping vs Kennedy | Akira Corassani | KO/TKO | Win |
| December 28, 2013 | UFC 168: Weidman vs Silva 2 | Diego Brandao | KO/TKO | Win |
| August 31, 2013 | UFC 164: Henderson vs Pettis 2 | Erik Koch | Decision - Unanimous | Win |
| February 16, 2013 | UFC on FUEL TV: Barao vs McDonald | Cub Swanson | Decision - Unanimous | Loss |
| December 15, 2012 | The Ultimate Fighter: Team Carwin vs. Team Nelson Finale | Jonathan Brookins | Submission | Win |
| May 15, 2012 | UFC on FUEL TV: Korean Zombie vs Poirier | Chan Sung Jung | Submission | Loss |
| February 04, 2012 | UFC 143: Diaz vs Condit | Max Holloway | Submission | Win |
| November 12, 2011 | UFC on FOX: Velasquez vs Dos Santos | Pablo Garza | Submission | Win |
| June 11, 2011 | UFC 131: Dos Santos vs Carwin | Jason Young | Decision - Unanimous | Win |
| January 01, 2011 | UFC 125: Resolution | Josh Grispi | Decision - Unanimous | Win |
| November 12, 2022 | UFC 281: Adesanya vs. Pereira | Michael Chandler | Submission | Win |